Mechanisms of Reciprocal Interactions between HIV Associated Neuroinflammation and Central Nervous System (CNS) Persistence: Implications in HIV Neuropathogenesis and Cure

The goal of this concept is to examine mechanisms of reciprocal interactions between HIV-associated neuroinflammation and central nervous system (CNS) persistence in the setting of excellent virologic control using novel CNS cell systems, organoid models, and single-cell technologies.